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AI tool helps find life-saving medicine for rare disease

AI tool helps find life-saving medicine for rare disease

Detailed in a new paper published in NEJM, a group led by researchers at the Perelman School of Medicine at the University of Pennsylvania used an AI technique called machine learning to determine that adalimumab -- a monoclonal antibody which is FDA-approved to treat conditions ranging from arthritis to Crohn's disease -- was the "top-predicted" new treatment that was likely to work for iMCD.


Relief could be on the way for UTI sufferers dealing with debilitating pain

Relief could be on the way for UTI sufferers dealing with debilitating pain

"We found that UTIs, caused by bacterial infections such as E. coli, can significantly alter the function and sensitivity of the nerves that usually detect bladder fulness, a phenomenon known as 'bladder afferent hypersensitivity', says Dr Grundy, from the College of Medicine and Public Health.


Value-added pancakes: Using science to improve nutrition of breakfast staple

Value-added pancakes: Using science to improve nutrition of breakfast staple

Food scientists are working to make pancakes healthier by boosting the popular morning favorite's nutritional value while enhancing its taste and texture.


How the brain enables flexible decisions

How the brain enables flexible decisions

"Flexibly associating different behaviors with a given situation is a core competence of our brain," explains Alexander Gail, head of the Sensorimotor Research Group and the study.


ECG tests may someday be used by AI model to detect premature aging and cognitive decline

ECG tests may someday be used by AI model to detect premature aging and cognitive decline

Answering this could lead to valuable treatments since some ECG issues can be fixed," said Fernando D. Testai, M.D., Ph.D., FAHA, chair of the October 2024 American Heart Association scientific statement Cardiac Contributions to Brain Health and professor of neurology and rehabilitation at the University of Illinois College of Medicine in Chicago.


New research unlocks key to long-lasting immune response in cancer and chronic diseases

New research unlocks key to long-lasting immune response in cancer and chronic diseases

The University of Melbourne's Catarina Gago da Graça, PhD Candidate at the Doherty Institute, said the research highlights how ID3+ T cells hold the key to overcoming one of the biggest challenges in treating chronic diseases -- immune exhaustion.


Weight-loss surgery lowers risk of developing complications of liver disease in patients with cirrhosis and obesity

Weight-loss surgery lowers risk of developing complications of liver disease in patients with cirrhosis and obesity

Steven Nissen, M.D., Chief Academic Officer of the Heart, Vascular and Thoracic Institute at Cleveland Clinic and the study's senior investigator, said: "Currently, lifestyle intervention is the only therapeutic recommendation for compensated MASH-related cirrhosis.


Predicting ‘male-time’ with the Androgen Clock

Predicting ‘male-time’ with the Androgen Clock

Associate Professor Tim Hore, research team leader in the Department of Anatomy, says there are many potential applications for the Androgen Clock in medicine, sports, and agriculture, including meat testing, as performed in the study.


PET probe images inflammation with high sensitivity and selectivity

PET probe images inflammation with high sensitivity and selectivity

June 13, 2021 — A new imaging technique has the potential to detect neurological disorders -- such as Alzheimer's disease -- at their earliest stages, enabling physicians to diagnose and treat patients more quickly.


Imagining the physics of George R.R. Martin’s fictional universe

Imagining the physics of George R.R. Martin’s fictional universe

"The fictional virus is really just an excuse to justify the world of Wild Cards, the characters who inhabit it, and the plot lines that spin out from their actions."


The 16 best nutritionist-backed protein bars we tested for every diet

The 16 best nutritionist-backed protein bars we tested for every diet

Now, it’s time to revisit that deep-dive into all the different brands and ingredients that are expert-backed to help you up your protein count in a healthy, balanced way — whether you’re looking for a pre-workout boost before hitting your rowing machine and treadmill or are looking to swap out unhealthy boxes in your pantry.


Advancements in neural implant research enhance durability

Advancements in neural implant research enhance durability

A team of researchers from the Bioelectronics Section led by Dr. Vasiliki (Vasso) Giagka, address this challenge by studying the degradation mechanisms of silicon ICs in the body and by coating them with soft PDMS elastomers to form body-fluid barriers that offer long-term protection to implantable chips.