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2025 February


AI tool helps find life-saving medicine for rare disease

AI tool helps find life-saving medicine for rare disease

Detailed in a new paper published in NEJM, a group led by researchers at the Perelman School of Medicine at the University of Pennsylvania used an AI technique called machine learning to determine that adalimumab -- a monoclonal antibody which is FDA-approved to treat conditions ranging from arthritis to Crohn's disease -- was the "top-predicted" new treatment that was likely to work for iMCD.


Relief could be on the way for UTI sufferers dealing with debilitating pain

Relief could be on the way for UTI sufferers dealing with debilitating pain

"We found that UTIs, caused by bacterial infections such as E. coli, can significantly alter the function and sensitivity of the nerves that usually detect bladder fulness, a phenomenon known as 'bladder afferent hypersensitivity', says Dr Grundy, from the College of Medicine and Public Health.


Value-added pancakes: Using science to improve nutrition of breakfast staple

Value-added pancakes: Using science to improve nutrition of breakfast staple

Food scientists are working to make pancakes healthier by boosting the popular morning favorite's nutritional value while enhancing its taste and texture.


How the brain enables flexible decisions

How the brain enables flexible decisions

"Flexibly associating different behaviors with a given situation is a core competence of our brain," explains Alexander Gail, head of the Sensorimotor Research Group and the study.


ECG tests may someday be used by AI model to detect premature aging and cognitive decline

ECG tests may someday be used by AI model to detect premature aging and cognitive decline

Answering this could lead to valuable treatments since some ECG issues can be fixed," said Fernando D. Testai, M.D., Ph.D., FAHA, chair of the October 2024 American Heart Association scientific statement Cardiac Contributions to Brain Health and professor of neurology and rehabilitation at the University of Illinois College of Medicine in Chicago.


New research unlocks key to long-lasting immune response in cancer and chronic diseases

New research unlocks key to long-lasting immune response in cancer and chronic diseases

The University of Melbourne's Catarina Gago da Graça, PhD Candidate at the Doherty Institute, said the research highlights how ID3+ T cells hold the key to overcoming one of the biggest challenges in treating chronic diseases -- immune exhaustion.