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Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

The study examined SARS-CoV-2 spike antigen-specific antibody-secreting cells (ASCs) in several bone marrow compartments in a cohort of 19 individuals up to three years following COVID-19 mRNA vaccination.