Immunotherapy efficacy can be boosted by preserving lymph nodes, crucial for T cell training. Research suggests lymph node removal during surgery may hinder cancer treatment response. Gut bacteria also influence immunotherapy.
Blocking macropinocytosis, a nutrient-scavenging process used by pancreatic cancer (PDAC) cells, reshapes the tumor microenvironment, enhancing immunotherapy and radiation effectiveness. This improves drug delivery and immune cell access.
Researchers developed a metal-free, blue light method using modified carbohydrates (thiosugars) to combat antibiotic-resistant infections, cancer, and gram-negative pathogens like Pseudomonas aeruginosa. This advance enhances drug delivery and reduces toxicity.
