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  • Immune System


    Type 1 Diabetes: New Insights into VAFs and Immune Response

    Type 1 Diabetes: New Insights into VAFs and Immune Response

    New research reveals vascular-associated fibroblastic cells (VAFs) role in type 1 diabetes. A $3.2M grant will explore VAFs, immune response, and potential treatments for this autoimmune disease.


    Cancer Immunotherapy: Boosting Immune Defenses for Tumor Regression

    Cancer Immunotherapy: Boosting Immune Defenses for Tumor Regression

    Johns Hopkins researchers found boosting immune defenses prevents cancer recurrence and boosts survival. Activating T and B cells transforms 'cold' tumors, enhancing immunotherapy and radiation treatment effectiveness.


    Endurance Training: Enhancing Immunity & Reducing Inflammation in Older Adults

    Endurance Training: Enhancing Immunity & Reducing Inflammation in Older Adults

    Long-lasting endurance training boosts the immune system in older adults by enhancing NK cell function, reducing inflammation, and improving metabolic control. Exercise combats cellular aging.


    Alzheimer’s Protein: A Surprising Cancer Fighter & Immune Booster

    Alzheimer’s Protein: A Surprising Cancer Fighter & Immune Booster

    Amyloid beta, a protein linked to Alzheimer's, strengthens T-cells, boosting immunity against cancer. Preserving mitochondria and managing fumarate are key. This reveals a potential link between Alzheimer's and cancer defense.


    Ischemia & Cancer: Blood Flow’s Impact on Tumor Growth

    Ischemia & Cancer: Blood Flow’s Impact on Tumor Growth

    Research reveals that restricted blood circulation (ischemia) drives cancer growth by reprogramming stem cells and impairing immune responses. Peripheral artery disease is linked to faster breast tumor growth.


    CPMV: Plant Virus Immunotherapy for Metastatic Cancer

    CPMV: Plant Virus Immunotherapy for Metastatic Cancer

    A plant virus (CPMV) shows promise as an immunotherapy against metastatic cancer in mice. It stimulates interferons and immune responses, offering a low-cost alternative for clinical trials. Cancer cells are destroyed.


    Spastic Paraplegia: Immune System’s Role in Brain Degeneration

    Spastic Paraplegia: Immune System’s Role in Brain Degeneration

    Research reveals immune system over-activation in spastic paraplegia type 15. Microglia changes and killer T-cells contribute to neuronal damage, suggesting potential immune-based therapies for this neurodegenerative disease.