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    • Michigan Rogel Cancer

    Research points to potential new treatment for aggressive prostate cancer subtype

    Research points to potential new treatment for aggressive prostate cancer subtype

    Then, when we added loss of the p53 oncogene, the mice developed bona fide invasive prostate cancer," said senior author Arul M. Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology and S.P.

    Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

    Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

    Researchers previously found loss of the CDK12 gene in about 7% of patients with metastatic prostate cancer, suggesting this alteration may be linked to a more-aggressive form of the disease.