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Rogel Cancer Center

Research points to potential new treatment for aggressive prostate cancer subtype

Research points to potential new treatment for aggressive prostate cancer subtype

Then, when we added loss of the p53 oncogene, the mice developed bona fide invasive prostate cancer," said senior author Arul M. Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology and S.P.

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

Researchers previously found loss of the CDK12 gene in about 7% of patients with metastatic prostate cancer, suggesting this alteration may be linked to a more-aggressive form of the disease.