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Causes of fevers of unknown origin in sub-Saharan Africa

Causes of fevers of unknown origin in sub-Saharan Africa

Early detection of the infectious causes of FUO is critical for patient care, effective response to outbreaks, and development of regionally appropriate diagnostics.


Inability of cells to recycle fats can spell disease

Inability of cells to recycle fats can spell disease

Led by Associate Professor Nguyen Nam Long, from the Department of Biochemistry and Immunology Translational Research Programme (TRP) at NUS Medicine, the team found that Spns1 is like a cellular gatekeeper which can help to move a type of fat molecule called lysophospholipids to the lysosome, the cell's "recycling centre."


Barbeque and grandma’s cookies: New study looks at nostalgia, comfort in food preparation for older adults

Barbeque and grandma’s cookies: New study looks at nostalgia, comfort in food preparation for older adults

Foods that evoke a sense of nostalgia and comfort and have good texture variety are important considerations in prepared meals aimed at older adults, according to new Washington State University research.


High-tech video optimization in our brain

High-tech video optimization in our brain

The three scientists and co-first authors Tomas Vega-Zuniga, Anton Sumser, and Olga Symonova combined a range of state-of-the-art techniques to identify a brain region in the mouse that can predict and minimize how movements distort the visual signal.


Potential new pathway to fight viruses

Potential new pathway to fight viruses

Oct. 19, 2022 — An international team of scientists who analyzed centuries-old DNA from victims and survivors of the Black Death pandemic has identified key genetic differences that determined who lived and who ...


AI tool helps find life-saving medicine for rare disease

AI tool helps find life-saving medicine for rare disease

Detailed in a new paper published in NEJM, a group led by researchers at the Perelman School of Medicine at the University of Pennsylvania used an AI technique called machine learning to determine that adalimumab -- a monoclonal antibody which is FDA-approved to treat conditions ranging from arthritis to Crohn's disease -- was the "top-predicted" new treatment that was likely to work for iMCD.


Relief could be on the way for UTI sufferers dealing with debilitating pain

Relief could be on the way for UTI sufferers dealing with debilitating pain

"We found that UTIs, caused by bacterial infections such as E. coli, can significantly alter the function and sensitivity of the nerves that usually detect bladder fulness, a phenomenon known as 'bladder afferent hypersensitivity', says Dr Grundy, from the College of Medicine and Public Health.


Value-added pancakes: Using science to improve nutrition of breakfast staple

Value-added pancakes: Using science to improve nutrition of breakfast staple

Food scientists are working to make pancakes healthier by boosting the popular morning favorite's nutritional value while enhancing its taste and texture.


How the brain enables flexible decisions

How the brain enables flexible decisions

"Flexibly associating different behaviors with a given situation is a core competence of our brain," explains Alexander Gail, head of the Sensorimotor Research Group and the study.


ECG tests may someday be used by AI model to detect premature aging and cognitive decline

ECG tests may someday be used by AI model to detect premature aging and cognitive decline

Answering this could lead to valuable treatments since some ECG issues can be fixed," said Fernando D. Testai, M.D., Ph.D., FAHA, chair of the October 2024 American Heart Association scientific statement Cardiac Contributions to Brain Health and professor of neurology and rehabilitation at the University of Illinois College of Medicine in Chicago.


New research unlocks key to long-lasting immune response in cancer and chronic diseases

New research unlocks key to long-lasting immune response in cancer and chronic diseases

The University of Melbourne's Catarina Gago da Graça, PhD Candidate at the Doherty Institute, said the research highlights how ID3+ T cells hold the key to overcoming one of the biggest challenges in treating chronic diseases -- immune exhaustion.


Weight-loss surgery lowers risk of developing complications of liver disease in patients with cirrhosis and obesity

Weight-loss surgery lowers risk of developing complications of liver disease in patients with cirrhosis and obesity

Steven Nissen, M.D., Chief Academic Officer of the Heart, Vascular and Thoracic Institute at Cleveland Clinic and the study's senior investigator, said: "Currently, lifestyle intervention is the only therapeutic recommendation for compensated MASH-related cirrhosis.